The Dionex ASE 350 is a used laboratory instrument — specifically an accelerated solvent extractor, sometimes referred to as a pressurised solvent extractor — designed to isolate target compounds from solid and semisolid sample matrices. Thermo Fisher Scientific's Dionex brand is well established in the analytical laboratory sector, producing instruments for chromatography, sample preparation, and related laboratory workflows across environmental, food science, pharmaceutical, and research applications. This unit is located in Poland and is offered at $10,000.
A defining capability of the ASE 350 is its ability to process up to 24 samples simultaneously, giving laboratories a meaningful increase in sample throughput compared with conventional extraction methods. The instrument achieves this by applying elevated temperatures and pressures during the extraction process, conditions that enhance solvent penetration into the sample matrix and improve the efficiency with which analytes are drawn out. This approach reduces both solvent consumption and overall extraction time relative to traditional techniques such as Soxhlet extraction.
Precise temperature and pressure control mechanisms are built into the system, maintaining optimal extraction conditions throughout each run. This level of control is central to generating reproducible, quantifiable results — a requirement in regulated analytical environments where method validation and data integrity are paramount. The instrument accommodates various sample sizes and types, making it adaptable to different matrices encountered in environmental monitoring, food testing, and pharmaceutical sample preparation.
The ASE 350 is equipped with intuitive software and automation capabilities that reduce the need for manual intervention during the extraction process. This automation minimises operator-introduced variability and supports consistent, reliable outputs across high-volume analytical workflows.
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